Frank Sams-Dodd, Ph.D., D.Sc.

Publication list (papers)

1. Dodd, F. and Capranica, R.R. (1992). A comparison of anesthetic agents and their effects on the response properties of the peripheral auditory system. Hearing Research, vol. 62, pp. 173-180.

2. Dodd, F. (1993) Neural networks in pharmacology: Models of mental disorders and the effects of drug treatments. Nordic Journal of Psychiatry Supplementum, vol. 47, pp. 17-26.

3. Sams-Dodd, F. and Capranica, R.R. (1994) Representation of Acoustic Signals in the Eighth Nerve of the Tokay Gecko: I. Pure Tones. Hearing Research, vol. 76, pp. 16-30.

4. Sams-Dodd, F. (1995) Distinct effects of d-amphetamine and phencyclidine on the social behaviour of rats. Behavioural Pharmacology, vol. 6, pp. 55-65.

5. Sams-Dodd, F. (1995) Automation of the social interaction test by a video tracking system: Behavioural effects of repeated phencyclidine treatment. Journal of Neuroscience Methods, vol. 59, pp. 157-167.

6. Sams-Dodd, F. (1996) Phencyclidine-induced stereotyped behaviour and social isolation in rats: A possible animal model of schizophrenia. Behavioural Pharmacology, vol. 7, pp. 3-23.

7. Sams-Dodd, F. and Capranica, R.R. (1996) Representation of Acoustic Signals in the Eighth Nerve of the Tokay Gecko: II. Masking of Pure Tones with White Noise. Hearing Research, vol. 100, pp. 131-142.

8. Sams-Dodd, F. and Newman, J.D. (1997) Effects of administration regime on the psychotomimetic properties of d-amphetamine in the squirrel monkey (Saimiri sciureus). Pharmacology Biochemistry and Behavior, vol. 56, pp. 471-480.

9. Andersen, M.B. and Sams-Dodd, F. (1997) Transient cerebral ischemia inhibits juvenile recognition in the mongolian gerbil. Pharmacology, Biochemistry and Behavior, vol. 56, pp. 719-725.

10. Sams-Dodd, F. (1997) The effects of novel antipsychotic drugs on PCP-induced stereotyped behaviour and social isolation in the rat social interaction test. Behavioural Pharmacology, vol. 8, pp. 196-215.

11. Sams-Dodd, F., Lipska, B.K. and Weinberger, D.K. (1997) Neonatal lesions of the rat ventral hippocampus result in hyperlocomotion and deficits in the social behaviour in adulthood. Psychopharmacology, vol 132, pp. 303-311.

12. Karle, J., Laudrup, P., Sams-Dodd, F., Mikkelsen, J. D. and Nielsen, M. (1997) Differential changes in seizure behaviour of rats following hippocampal antisense knockout of the GABAA receptor g2 subunit. European Journal of Pharmacology, vol 340, pp. 153-160.

13. Andersen, M.B., Zimmer, J. and Sams-Dodd, F. (1997) Post-ischemic hyperactivity in the mongolian gerbil correlates to loss of pyramidal cells in the hippocampal CA subfields. Behavioural Neuroscience, vol. 111, pp. 1205-1216.

14. Sams-Dodd, F. (1998) The effects of dopamine agonists and antagonists on PCP-induced stereotyped behaviour and social isolation in rats. Psychopharmacology, vol. 135, pp. 182-193.

15. Sams-Dodd, F. (1998) A test of the predictive validity of animal models of schizophrenia based on phencyclidine and d-amphetamine. Neuropsychopharmacology, vol. 18, pp. 293-304.

16. Andersen, M.B. and Sams-Dodd, F. (1998) Impairment of working memory in the T-maze after transient cerebral ischemia in the mongolian gerbil. Behavioural Brain Research, vol. 91, pp. 15-22.

17. Sams-Dodd, F. (1998) Effects of continuous d-amphetamine or phencyclidine administration on social behaviour, stereotyped behaviour and locomotor activity in rats. Neuropsychopharmacology, vol. 19, pp.18-25.

18. Sams-Dodd, F. (1998) Effects of diazepam, citalopram, methadone and naloxone on PCP-induced stereotyped behaviour and social isolation in the rat social interaction test. Neuroscience and Biobehavioural Reviews, vol. 23, pp. 287-293.

19. Andersen, M.B., Zimmer, J. and Sams-Dodd, F. (1999) Specific behavioural effects related to age and cerebral ischemia rats. Pharmacology, Biochemistry and Behavior, vol. 62, pp. 673-82.

20. Sams-Dodd, F. (1999) Phencyclidine in the social interaction test: An animal model of schizophrenia with face and predictive validity. Reviews in the Neurosciences, vol. 10, pp. 59-90.

21. Ellenbroek, B.A., Sams-Dodd, F., and Cools, A.R. (2000) Simulation models for schizophrenia. In: Atypical antipsychotics, eds. B.A. Ellenbroek & A.R. Cools, Birkhauser Verlag, Basel, pp. 121-142.

22. Sams-Dodd, F. (2004) (+) MK-801 and Phencyclidine Induced Neurotoxicity do Not Cause Enduring Behaviours Resembling the Positive and Negative Symptoms of Schizophrenia in the Rat. Basic & Clinical Pharmacology & Toxicology, vol. 95, pp. 241-246.

23. Sams-Dodd, F. (2005) Target-based drug discovery: Is something wrong? Drug Discovery Today, vol. 10 (2), pp. 139-147.

24. Sams-Dodd, F. (2005) Optimising the Discovery Organisation for Innovation. Drug Discovery Today, vol. 10 (15), pp. 1049-1056.

25. Sams-Dodd, F. (2006) Strategies to optimize the validity of disease models in the drug discovery process. Drug Discovery Today, vol. 11(7/8), pp. 355-363.

26. Sams-Dodd, F. (2006) Drug Discovery: Selecting the Optimal Approach. Drug Discovery Today, vol. 11 (9/10), pp. 465-472.

27. Larsen, M.H., Rosenbrock, H., Sams-Dodd, F. and Mikkelsen, J.D. (2007) Expression of brain derived neurotrophic factor (BDNF), activity-regulated cytoskeleton protein (Arc) mRNA, and enhancement of adult hippocampal neurogenesis in rats after sub-chronic and chronic treatment with the triple monoamine re-uptake inhibitor tesofensine (NS2330). European Journal of Pharmacology, vol. 555, pp. 115-121.

28. Koros, E., Rosenbrock, H., Weiss, C. and Sams-Dodd, F. (2007) The selective mGlu5 receptor antagonist MTEP, similar to NMDA receptor antagonists, induces social isolation in rats. Neuropsychopharmacology, vol. 32 (3), pp. 562-576

29. Sams-Dodd, F. (2007) Research & Market Strategy: How Choice of Drug Discovery Approach can affect Market Position. Drug Discovery Today, vol. 12 (7/8), pp. 314-318.
 

Patents

1. Sams-Dodd, F. and Arnt, J. (1998) Treatment of schizophrenia and psychosis. International Application no. PCT/DK98/00220.

2. Bornemann, K., Trummlitz, G., Beck, B., Sams-Dodd, F., Kugler, D., Klinder, K., Dorner-Ciossek, C. and Kostka, M. (2005) Method of treating diseases and conditions associated with an altered level of amyloid beta peptides and new enolcarboxamide compounds. EP 04011894.5, USPA 20050277635

3. Bornemann, K., Trummlitz, G., Lazer, ES, Miao, C.K., Beck, B., Sams-Dodd, F., Kugler, D., Klinder, K., Dorner-Ciossek, C., Kostka, M. (2006) Method of treating diseases and conditions associated with an altered level of amyloid beta peptides and new enolcarboxamide compounds. USPA 20060040928

 

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